The Boulder Laboratory for 3-Dimensional Electron
Microscopy of Cells is located in the Department of Molecular,
Cellular, and Developmental Biology at the University of Colorado.
It is a National Resource Center supported by the National
Center for Research Resources (NCRR) at the National Institutes
of Health (NIH).
The Boulder Facility is devoted to the development of new
technologies for specimen preparation and image analysis to
study the three-dimensional structure of cells and tissues.
Techniques for rapid-freezing and freeze-substitution of samples,
immunolabeling, serial-sectioning and high-resolution electron
tomography are employed and advanced in the facility.
The primary imaging tools of this facility are two FEI Tecnai
intermediate voltage electron microscopes operating at 200,000
and 300,000 volts. |